SELF-HEALING ADHESIVE OXIDIZED GUAR GUM HYDROGEL LOADED WITH MESENCHYMAL STEM CELL EXOSOMES FOR CORNEAL WOUND HEALING

Self-healing adhesive oxidized guar gum hydrogel loaded with mesenchymal stem cell exosomes for corneal wound healing

Abstract Hydrogels have shown great potential and value in wound healing.In this study, we construct a mesenchymal stem cell exosomes (MSC-Exos) laden natural biopolymer-based hydrogel with transparent, self-healing, injectable, and tissue adhesive properties to promote corneal regeneration.This hydrogel is synthesized by combining aldehyde-modifie

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Informed Bayesian survival analysis

Abstract Background We provide an overview of Bayesian estimation, hypothesis testing, and model-averaging and illustrate how they benefit parametric survival analysis.We contrast the Bayesian framework to the currently dominant frequentist approach and highlight advantages, such as seamless incorporation of historical data, continuous monitoring o

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